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[Optimal care for chronic renal failure in the elderly]
1Service de néphrologie, hôpitaux de Brabois, CHU de Nancy, 54500 Vandoeuvre-lès-Nancy. m.kessler@chu-nancy.fr
Chronic kidney disease (CKD) is increasing in older adults, often diagnosed late. Early detection and management are crucial to slow progression, prevent complications, and improve quality of life.
Area of Science:
- Nephrology
- Geriatrics
- Public Health
Context:
- Growing incidence and prevalence of chronic kidney disease (CKD) in elderly populations in developed nations.
- Progression to end-stage renal failure (ESRF) in this demographic presents a significant public health challenge.
- Late referral of elderly chronic renal failure (CRF) patients to nephrology units results in suboptimal care.
Purpose:
- To outline essential strategies for managing CKD in the elderly.
- To emphasize early identification and intervention for kidney disease.
- To improve patient outcomes and quality of life for elderly individuals with CRF.
Summary:
- Key management goals include early CKD detection, slowing CRF progression, and managing complications like hypertension, anemia, and mineral and bone disorders.
- Controlling comorbidities, especially cardiovascular disease, is vital.
- Informing patients and families about renal replacement therapies (RRT) and preparing them for indicated RRT is essential.
Impact:
- Aims to retard or avoid the need for RRT in elderly patients.
- Focuses on decreasing morbidity and mortality associated with CKD.
- Prioritizes maintaining a good quality of life for aging individuals with kidney disease.
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Reduced renal clearance and elimination rate are common outcomes of renal impairment. These alterations lead to a prolonged elimination half-life and an altered apparent volume of distribution for drugs. As a result, dosage adjustments are typically necessary to maintain optimal drug levels in the body.
However, dosage adjustments...