Related Experiment Video
Updated: Aug 10, 2026

Osmotic Minipump Implantation for Increasing Glucose Concentration in Mouse Cerebrospinal Fluid
Published on: April 7, 2023
[Cranial diabetes insipidus in Wegener's granulomatosis]
Jesper Moesgaard1, Kasper Kjaehr, Bjarne Svalgaard Thomsen
1Arhus Sygehus, Medicinsk Afdeling M, Arhus C.
Abstract:
We describe three cases of cranial diabetes insipidus (CDI) caused by Wegener's granulomatosis (WG). Panhypopituitarism was the presenting symptom in one patient. Magnetic resonance imaging (MRI) showed enlargement of the pituitary gland with an intrasellar mass lesion and absence of posterior pituitary lobe hyperintensity. Follow-up MRI disclosed reduction of the intrasellar lesion but sustained loss of posterior lobe hyperintensity. The patients still have CDI despite a marked clinical response to the treatment of WG. Pituitary dysfunction may be the presenting symptom as well as a complication of WG.
Related Concept Videos
Type I Diabetes III: Clinical Manifestations
Type I Diabetes I: Introduction
Type I Diabetes II: Pathophysiology
Diabetic Neuropathy
Diabetic Retinopathy
Diabetes: Symptoms, Diagnosis, and Complications

