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Synthesis and application of a fluorous Lawesson's reagent: convenient chromatography-free product purification
Zoltan Kaleta1, Gabor Tarkanyi, Agnes Gömöry
1Institute of Biomolecular Chemistry, Chemical Research Center of the Hungarian Academy of Science, P.O. Box 17, 1525 Budapest, Hungary.
Abstract:
[reaction: see text] A fluorous analogue of Lawesson's reagent for thionation of carbonyl compounds has been developed and its use demonstrated on a series of amides, esters, and ketones. The separation of the Lawesson's reagent-derived byproducts can be achieved by a simple fluorous solid-phase extraction.
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