Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Carcinoid heart disease.

Heidi M Connolly1, Patricia A Pellikka

  • 1Mayo Clinic, 200 First Street, SW, Rochester, MN 55905, USA. connolly.heidi@mayo.edu

Current Cardiology Reports
|March 10, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Clinical benefit of optimization of heart failure therapy after heart failure hospitalization in adults with CHD.

International journal of cardiology. Congenital heart disease·2026
Same author

Outcomes of liver resections for neuroendocrine tumor liver metastases in carcinoid heart disease.

Journal of neuroendocrinology·2026
Same author

Reoperations after the Ross procedure: Techniques, complexity, and outcomes.

JTCVS structural and endovascular·2026
Same author

Prognostic Value of Left Ventricular Contractility Index in Patients with Coarctation of Aorta and Preserved Ejection Fraction.

American heart journal·2026
Same author

Outcome of Heart Failure Therapy in Adults With Congenitally Corrected Transposition of Great Arteries.

JACC. Heart failure·2026
Same author

Ten-year outcomes of valve-replacing versus valve-sparing aortic root replacement in patients with Marfan syndrome: An observational multicenter study.

The Journal of thoracic and cardiovascular surgery·2026
Same journal

Diagnostic Tests for Stage B Heart Failure.

Current cardiology reports·2026
Same journal

Cardioimmunology of Myocarditis: Targeting the IL-1 Pathway.

Current cardiology reports·2026
Same journal

Antithrombotic Management in Patients with Chronic Coronary Syndrome Receiving Oral Anticoagulation.

Current cardiology reports·2026
Same journal

Transcriptome Reprogramming in Heart Failure: The Hidden Splicing Code.

Current cardiology reports·2026
Same journal

Diagnosis and Management of Loeys-Dietz Syndrome: Evidence Gaps and Future Directions.

Current cardiology reports·2026
Same journal

Correction: Heart Disease in Older Women: Unique Challenges in Diagnosis and Management.

Current cardiology reports·2026
See all related articles

Carcinoid heart disease significantly impacts survival, but aggressive surgical management of severe valvular issues can dramatically improve patient function. Early cardiac surgery is recommended for symptomatic patients with controlled carcinoid syndrome.

Area of Science:

  • Cardiology
  • Oncology
  • Cardiothoracic Surgery

Background:

  • Carcinoid disease, particularly malignant carcinoid syndrome, poses significant risks.
  • Carcinoid heart disease is a primary driver of morbidity and mortality in these patients.
  • Effective medical therapies for symptomatic carcinoid heart disease are limited.

Purpose of the Study:

  • To evaluate the outcomes of an aggressive surgical approach to severe valvular dysfunction in carcinoid heart disease.
  • To determine optimal timing for cardiac intervention in patients with carcinoid heart disease.
  • To highlight the importance of a multidisciplinary team in managing carcinoid heart disease.

Main Methods:

  • Review of patients with severe valvular dysfunction due to carcinoid heart disease undergoing cardiac operations.

Related Experiment Videos

  • Analysis of factors influencing surgical outcomes, including patient age and functional class.
  • Assessment of functional capacity improvement post-surgery.

    • Main Results:

    • Cardiac surgery survivors typically experience dramatic improvements in functional capacity.
    • Surgical outcomes are influenced by patient age and functional class at the time of operation.
    • Early surgical consideration is associated with better outcomes for symptomatic patients.

    Conclusions:

    • Aggressive surgical management of severe valvular dysfunction in carcinoid heart disease leads to significant functional improvement.
    • Cardiac surgery should be considered early in patients with symptomatic carcinoid heart disease and controlled carcinoid symptoms.
    • A multidisciplinary team approach is crucial for optimal management of carcinoid heart disease.