Ion exchange reaction of [18F]fluoride with an oxidized carbon surface
1Department of Internal Medicine, University of Michigan Medical School, Ann Arbor 48109-0552.
Abstract:
[18F]Fluoride was trapped from [18O]water in high yield by ion exchange on a microporous carbon prepared by controlled oxidation to produce a cationic surface with an exchange capacity of about 350 microequiv/g. The [18F]fluoride could be recovered by displacement with aqueous K2CO3. The cationic carbon offered a dimensionally rigid matrix of high thermal stability. It was characterized with respect to chemical reactivity and selectivity for anion exchange.
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