New hope for Treacher-Collins syndrome: a surgical case report

The objective of this case report is to discuss the possibility of developing a surgical treatment paradigm for patients with some of the noted characteristics of Treacher-Collins syndrome, mainly mandibular ankylosis and/or retrognathia (mandibular retrusion), in a way that would provide lasting, predictable results and minimize the frequently seen mandibular ankylosis. Through various medical imaging techniques, mainly computed tomography (CT) scan, the radiology imaging technologist produces accurate CT scan images of the particular patient's osseous cranial structures. These images can then be used by the stereolithography (SLA) technician to construct accurate SLA models. The SLA models can then be used by the surgical and implant design team to not only prescribe the surgical correction necessary, but also design and construct the actual temporomandibular joint (TMJ) and mandibular implants, as well as perform mock surgery, which will be needed to restore function and esthetics for the patient. The early results from this alloplastic reconstructive surgery have provided the anticipated results of relieving the ankylosis, improving jaw function and frequently dental occlusion, as well as improving the esthetics. Without this breakthrough surgical development, many of these Treacher-Collins syndrome patients will not be able to enjoy normal breathing, mastication, jaw function, esthetics, oral and dental health, and the emotional relief these corrections allow. Many patients who suffer the disfiguring and functionally damaging affects of Treacher-Collins syndrome never receive the surgical correction necessary. Many have had autogenous reconstruction of missing mandibular and TMJ structures, only to sometimes relapse into a more disfiguring and lasting condition. By simply placing a Christensen Fossa-Eminence Prosthesis(r) (TMJ Implants, Inc., Golden CO, USA) between the cranial base and any bone graft, one is more likely to achieve satisfactory TMJ mobility. If a condylar or mandibular reconstruction is necessary, the Christensen Total TMJ Prostheses(r) (TMJ Implants, Inc., Golden CO, USA) are available and provide excellent results.