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Updated: Aug 10, 2026
06:38
A Syngeneic Mouse Model of Metastatic Renal Cell Carcinoma for Quantitative and Longitudinal Assessment of Preclinical Therapies
Published on: April 12, 2017
[Kidney cancer local recurrence after 20 years]
Michał Tkocz1, Andrzej Szedel, Kamil Bochynek
1Z Oddziału Urologii Szpitala im Prof E Michałowskiego w Katowicach.
Wiadomosci Lekarskie (Warsaw, Poland : 1960)
|March 15, 2006
Summary
Late kidney cancer recurrence is rare, often asymptomatic, and detected incidentally. This case report details the first documented instance of local kidney cancer recurrence 20 years post-nephrectomy.
Area of Science:
- Oncology
- Urology
Background:
- Kidney cancer (renal cell carcinoma) recurrence after nephrectomy can occur, but late recurrences are exceptionally rare.
- Standard treatment for kidney cancer involves surgical removal (nephrectomy), often followed by immunotherapy and radiotherapy.
Observation:
- A patient presented with a local recurrence of kidney cancer 20 years after initial nephrectomy.
- The recurrence was asymptomatic and incidentally discovered during an ultrasonography examination.
- Diagnostic imaging, including computed tomography, was used to characterize the recurrent tumor.
Findings:
- This represents the first reported case of a local kidney cancer recurrence occurring 20 years after nephrectomy in the global medical literature.
- The case highlights the potential for extremely late malignant recurrence even after a long disease-free interval.
Implications:
- This case underscores the importance of long-term surveillance for patients treated for kidney cancer.
- It may prompt re-evaluation of follow-up protocols for extremely late recurrences.
- Understanding the biology of such rare, late recurrences could inform future treatment strategies.
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