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Use of Two Intracorporeal Ventricular Assist Devices As a Total Artificial Heart
Published on: May 11, 2018
[Mechanical cardiac assistance and artificial heart: historical perspectives]
E Flecher1, T Joudinaud, J-M Grinda
1Service de chirurgie cardiovasculaire, hôpital européen Georges-Pompidou, 20-40, rue Leblanc, 75015 Paris, France. erwan.flecher@wanadoo.fr
Insights
Artificial hearts offer a lifeline for end-stage heart failure patients awaiting transplants. These devices restore circulation, enabling patients to await transplantation at home, easing the donor organ shortage.
Area of Science:
- Cardiovascular Medicine
- Biomedical Engineering
- Medical Devices
Context:
- Growing impact of heart failure on patients and healthcare systems.
- Cardiac transplantation remains the primary treatment for end-stage heart failure.
- Shortage of donor organs and long waiting lists for cardiac transplantation.
Purpose:
- To review the development and application of artificial hearts.
- To highlight technical advancements in artificial heart technology.
- To discuss the potential of artificial hearts as destination therapy.
Summary:
- Artificial hearts (total and partial) were developed due to donor organ scarcity.
- Technical progress since 1957 allows patients to have circulation restored and await transplantation at home.
- Encouraging results and device miniaturization suggest artificial hearts as destination therapy for ineligible transplant candidates.
Impact:
- Provides a viable circulatory support option for end-stage heart failure patients.
- Addresses the critical shortage of donor hearts for transplantation.
- Offers potential for improved quality of life and extended survival for patients ineligible for transplantation.
Abstract:
The impact of heart failure on patients and economical burden on health insurance resources is increasing. Cardiac transplantation is still the primary treatment for patients who are in end stage heart failure. The development of artificial hearts (total and partial) was implemented by the discrepancy between the scarcity of available donors and the importance of waiting lists for cardiac transplantation. The technical progresses achieved since the first works of Kolff in 1957 now allow these patients to have their circulation restored and go home to wait for their transplantation. The encouraging results of the artificial heart and the miniaturization of these devices allow them to be considered as a possible destination therapy for patients not eligible for cardiac transplantation.
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