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Updated: Aug 10, 2026

Assessment of Child Anthropometry in a Large Epidemiologic Study
Published on: February 2, 2017
Failure to thrive: the prevalence and concurrence of anthropometric criteria in a general infant population
E M Olsen1, J Petersen, A M Skovgaard
1Research Centre for Prevention and Health, Glostrup University Hospital, Glostrup, Denmark. emao@glostruphosp.kbhamt.dk
Insights
Failure to thrive (FTT) definitions lack consensus, impacting accurate identification of undernutrition in infants. Studies show poor agreement between criteria, highlighting the need for better diagnostic tools for early childhood development.
Area of Science:
- Pediatric Nutrition
- Child Development
- Growth Monitoring
Background:
- Failure to thrive (FTT) in early childhood is linked to developmental delays and undernutrition.
- Current FTT definitions lack consensus, creating ambiguity in diagnosis.
- The concurrence of various anthropometric definitions for FTT is not well understood.
Purpose of the Study:
- To compare the prevalence and agreement of different anthropometric criteria for FTT.
- To evaluate the sensitivity and positive predictive values of FTT criteria in identifying significant undernutrition.
- To define significant undernutrition as slow weight gain and low body mass index (BMI).
Main Methods:
- Applied seven FTT criteria to a cohort of 6090 Danish infants.
- Included criteria such as low weight-for-age, low BMI, low conditional weight gain, and Waterlow's criterion.
- Compared criteria across two infant age groups: 2-6 months and 6-11 months.
Main Results:
- 27% of infants met at least one FTT criterion in either age group.
- Inter-criterion agreement was generally poor, with most infants identified by a single criterion.
- Positive predictive values ranged from 1% to 58%, with most single criteria failing to accurately identify significant undernutrition.
Conclusions:
- No single anthropometric measurement is sufficient for identifying nutritional growth delay.
- Further longitudinal studies are required to assess the effectiveness of different criteria in detecting undernutrition and predicting outcomes.
Background:
Failure to thrive (FTT) in early childhood is associated with subsequent developmental delay and is recognised to reflect relative undernutrition. Although the concept of FTT is widely used, no consensus exists regarding a specific definition, and it is unclear to what extent different anthropometric definitions concur.
Objective:
To compare the prevalence and concurrence of different anthropometric criteria for FTT and test the sensitivity and positive predictive values of these in detecting children with "significant undernutrition", defined as the combination of slow conditional weight gain and low body mass index (BMI).
Methods:
Seven criteria of FTT, including low weight for age, low BMI, low conditional weight gain and Waterlow's criterion for wasting, were applied to a birth cohort of 6090 Danish infants. The criteria were compared in two age groups: 2-6 and 6-11 months of life.
Results:
27% of infants met one or more criteria in at least one of the two age groups. The concurrence among the criteria was generally poor, with most children identified by only one criterion. Positive predictive values of different criteria ranged from 1% to 58%. Most single criteria identified either less than half the cases of significant undernutrition (found in 3%) or included far too many, thus having a low positive predictive value. Children with low weight for height tended to be relatively tall.
Conclusions:
No single measurement on its own seems to be adequate for identifying nutritional growth delay. Further longitudinal population studies are needed to investigate the discriminating power of different criteria in detecting significant undernutrition and subsequent outcomes.
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