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Published on: June 7, 2015
[Research on intelligent controlled drug delivery with polymer]
Zhibin Zhang1, Changwei Tang, Huiqing Chen
1Bioengineering Department, Southwest Jiaotong University, Chengdu, China.
Summary
Intelligent controlled drug delivery systems utilize smart polymers in micro/nanocapsules to respond to external stimuli like pH or temperature, enabling precise medication release. This review covers their synthesis and applications.
Area of Science:
- Polymer Science
- Materials Science
- Biomedical Engineering
Context:
- Intelligent controlled drug delivery systems (ICDDS) represent advanced pharmaceutical preparations.
- These systems often involve microcapsules or nanocapsules formulated with intelligent polymers and active pharmaceutical ingredients.
Purpose:
- To review the current research on the synthesis and applications of intelligent controlled drug delivery systems.
- To highlight the role of intelligent polymers in responsive drug delivery.
Summary:
- ICDDS formulations can alter their properties in response to external stimuli such as pH, temperature, chemical substances, light, electricity, and magnetism.
- This responsiveness allows for the intelligent control of drug release kinetics and targeting.
- The review encompasses various synthesis strategies and diverse application areas for these advanced polymer-based systems.
Impact:
- Provides a comprehensive overview of the field for researchers and developers.
- Facilitates the understanding of stimuli-responsive polymer behavior in drug delivery.
- Informs future research directions for developing more effective and targeted therapeutic interventions.
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