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Diagnosis and treatment of oral candidosis
M A Lewis1, L P Samaranyake, P J Lamey
1Department of Oral Medicine and Pathology, Glasgow Dental Hospital and School, Scotland.
Abstract:
Oral candidosis is a common opportunistic infection that manifests in a variety of forms. It is also recognized as one of the earliest manifestations of human immunodeficiency virus (HIV) infection. Although a number of antifungal agents are available for the treatment of this condition, a newly introduced triazole group of drugs appears to be highly effective in treating oral candidosis. This article reviews the clinical presentation and management of oral candidosis, particularly with reference to the latter group of drugs and HIV-induced disease.
Insights
Oral candidosis, an opportunistic infection, is an early sign of human immunodeficiency virus (HIV) infection. New triazole drugs show high effectiveness in treating oral candidosis, especially HIV-induced cases.
Area of Science:
- Infectious Diseases
- Mycology
- HIV/AIDS
Background:
- Oral candidosis is a frequent opportunistic infection with diverse clinical presentations.
- It serves as an early indicator of human immunodeficiency virus (HIV) infection.
- Existing antifungal treatments have limitations.
Purpose of the Study:
- To review the clinical presentation of oral candidosis.
- To discuss the management of oral candidosis, focusing on novel triazole antifungals.
- To highlight the significance of oral candidosis in HIV-induced disease.
Main Methods:
- Literature review of clinical presentations and management strategies.
- Focus on the efficacy of the triazole class of antifungal drugs.
- Examination of oral candidosis in the context of HIV infection.
Main Results:
- Oral candidosis presents in various forms and is an early marker for HIV.
- Newly introduced triazole antifungal agents demonstrate significant effectiveness.
- The triazole group offers a promising therapeutic option for oral candidosis.
Conclusions:
- Oral candidosis requires careful clinical evaluation and management.
- Triazole antifungals represent a highly effective treatment modality.
- Early detection and treatment are crucial, particularly in HIV-positive individuals.