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Updated: Aug 10, 2026
Application of Hemostatic Devices in Laparoscopic Hepatectomy
Published on: April 19, 2022
[Clinical features and treatment of hepatic tumor-like lesions]
Rong-Ping Guo1, Chong Zhong, Ming Shi
1State Key Laboratory of Oncology in South China, Guangzhou, Guangdong 510060, P. R. China. rpguo@gzsums.edu.cn
Background & Objective:
Focal nodular hyperplasia (FNH), inflammatory pseudotumor (IPT), adenomatous nodular hyperplasia (ANH), and focal fatty change (FFC) are common hepatic tumor-like lesions, a group of benign liver diseases, which remains difficult to be distinguished from primary liver cancer (PLC). This study was to investigate the clinical features and treatment of these 4 kinds of hepatic tumor-like lesions.
Methods:
Clinical data of 70 patients with pathologically conformed hepatic tumor-like lesions, treated in Cancer Center of Sun Yat-sen University from 1992 to 2004, were studied retrospectively.
Results:
Of the 70 patients, 34 (48.6%) had clinical symptoms, and most of them suffered mild pain in the abdomen; 22 (31.4%) were positive for hepatitis B virus (HBV) antigen; 21 had mild abnormal liver function; 6 had alpha fetal protein (AFP) > 25 microg/L. The ultrasonography and computed tomography (CT) presentations of the tumor-like lesions were various. Only 8 cases of FNH were diagnosed preoperatively. Sixty-one patients received resection, with no postoperative complication occurred. One case of FNH and 1 case of IPT were recurred during follow-up, and treated with non-resection therapy.
Conclusions:
Hepatic tumor-like lesions are difficult to be distinguished from PLC. Exploratory operation should be performed in cases suspicious of PLC.
