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Rescue and Characterization of Recombinant Virus from a New World Zika Virus Infectious Clone
Published on: June 7, 2017
[Rubella: a new scenario for an old disease]
Juan Carlos Sanz1, Fernando de Ory
1Laboratorio Regional de Salud Pública, Instituto de Salud Pública de la Comunidad de Madrid, Spain.
High measles-mumps-rubella vaccine coverage protects against rubella. However, immigration is increasing the number of susceptible adults, potentially allowing the virus to re-circulate.
Area of Science:
- Virology
- Immunology
- Public Health
Context:
- Rubella virus circulation control is essential for achieving the World Health Organization's 2010 target of reducing congenital rubella syndrome.
- Rubella is a low-incidence disease in developed countries due to high vaccination rates in children and women of childbearing age.
- Historically, young unvaccinated men represented the primary susceptible population.
Purpose:
- To analyze the impact of immigration on the rubella susceptibility patterns.
- To identify potential shifts in the demographic distribution of individuals susceptible to rubella.
- To assess the risk of rubella virus re-circulation in the context of changing population demographics.
Summary:
- Despite high measles-mumps-rubella (MMR) vaccine coverage in children and vaccination campaigns for women, immigration introduces a new challenge to rubella control.
- Immigrants from regions with low or no rubella vaccination programs may increase the pool of susceptible adults.
- This demographic shift could lead to the re-emergence and circulation of the rubella virus.
Impact:
- Highlights the need for updated vaccination strategies to address the susceptibility of adult immigrant populations.
- Informs public health policies regarding rubella surveillance and control in diverse demographic settings.
- Emphasizes the importance of considering migration patterns in infectious disease control efforts.
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