[Study on the levels of immunoglobulin in gingival cervicular fluid.]

The levels of IgG,IgA in gingival cervicular fluid (GCF) and serum were measured by immunodiffusion method.GCF was collected in improved and graduated capillaries from 50 healthy persons and 32 adult periodontitis patients (AP).The result showed that the level of IgG in GCF of healthy persons was 1.96g/L and the ratio of IgG in GCF to that in serum was 19%.The level of IGA in GCF of healthy persons was not available.In AP,the levels of IgG,IgA in GCF were 7.2g/L,0.83g/L and the ration of IgG and IgA in GCF to those in serum were 71%,61% respectively.Rank correlation between Ig and clinic index in AP showed thant only the level of IgG in GCF had positive correlation with GI.This study reported for the first time the level of IgG in GCF of healthy persons and suggested that the level of IgG in GCF had positive correlation with degree of inflammation in gingiva.