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Published on: August 7, 2017
[Evaluation of allergic prevalence in prematurely born children]
Anna Stańczyk-Przyłuska1, Iwona Ligenza, Jarosław Wlazłowski
1Klinika Propedeutyki Pediatrii i Chorób Metabolicznych Kości Uniwersytetu Medycznego w Lodzi.
Insights
Premature birth and prolonged oxygen support may increase asthma risk in children. However, atopic dermatitis was more common in children born at term, suggesting complex links between birth factors and allergic disease development.
Area of Science:
- Pediatric Allergy and Immunology
- Neonatal Medicine
- Clinical Immunology
Context:
- Premature birth is associated with potential long-term health issues.
- Prolonged oxygen supplementation in neonates is a common practice.
- Allergic diseases represent a significant public health concern in childhood.
Purpose:
- To investigate the association between premature delivery and prolonged oxygen supplementation with the prevalence of allergic diseases.
- To compare asthma and atopic dermatitis rates in prematurely born children versus those born at term.
- To analyze immunoglobulin E (IgE) levels in relation to allergic outcomes.
Summary:
- A retrospective study analyzed 60 prematurely born children and 30 term-born controls (all aged 4 years).
- Asthma prevalence was double in prematurely born children (33%) compared to term-born children (17%).
- Atopic dermatitis was more prevalent in term-born children (53%) than in prematurely born children (23%).
Impact:
- Findings suggest a differential impact of prematurity on specific allergic diseases.
- Highlights the need for further research into the mechanisms linking neonatal care and childhood allergies.
- Informs clinical monitoring and potential early interventions for high-risk infants.
Abstract:
Several data from literature suggest the potential influence of premature delivery with prolonged oxygen suplementation on prevalence of development of allergic diseases in children. The objective of the study was the retrospective analysis of 60 children aged 4 years, prematurely born, and 30 healthy children at the same age (the control group), born at term. In all children, beside detail interview and accurately clinical examination, the estimation of total IgE and specific IgE with chosen inhaled and food allergens was done. The obtained results of the studies shown twice as much prevalence of asthma in prematurely born children (33%) in comparison to these born at term (17%). However atopic dermatitis was observed more often in term children (53%) than in prematurely born children (23%).
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