Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Child thyroid disruption by environmental chemicals.

F Massart1, G Massai, G Placidi

  • 1Pediatric Endocrine Center, Department of Pediatrics, University of Pisa, Pisa, Italy. massart@med.unipi.it

Minerva Pediatrica
|March 17, 2006
PubMed
Summary

Environmental chemicals can disrupt thyroid function, impacting brain development in children. Exposure during pregnancy poses risks for irreversible neurological effects in offspring due to altered thyroid hormone levels.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Retraction Note: Autoantibodies detection in patients affected by autoimmune retinopathies.

European review for medical and pharmacological sciences·2024
Same author

Autoantibodies detection in patients affected by autoimmune retinopathies.

European review for medical and pharmacological sciences·2023
Same author

PERG adaptation for detection of retinal ganglion cell dysfunction in glaucoma: a pilot diagnostic accuracy study.

Scientific reports·2021
Same author

Classification strategies for a single-trial binary Brain Computer Interface based on remembering unpleasant odors.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2016
Same author

Poststreptococcal acute glomerulonephritis presenting as posterior reversible encephalopathy syndrome in an eleven-year-old boy.

Minerva pediatrica·2015
Same author

17q12 microduplications: a challenge for clinicians.

American journal of medical genetics. Part A·2015

Area of Science:

  • Endocrinology
  • Environmental Health
  • Developmental Neuroscience

Background:

  • Thyroid function is crucial for mammalian brain development.
  • Environmental chemicals are known to alter thyroid hormone levels.
  • Endocrine disruption from pollutants is a significant public health concern.

Purpose of the Study:

  • To review how environmental chemicals interfere with thyroid hormone production, metabolism, and excretion.
  • To discuss the impact of these disruptions on the thyroid system during child development.

Main Methods:

  • Review of laboratory experiments and animal studies.
  • Analysis of human and wildlife tissue samples.
  • Synthesis of clinical evidence on thyroid hormone sensitivity during development.

Related Experiment Videos

Main Results:

  • Chemicals commonly found in the environment can affect thyroid function.
  • Thyroid hormone imbalances during development can lead to permanent neurological deficits.
  • Maternal thyroid disruption impacts fetal brain development and offspring neurological outcomes.

Conclusions:

  • Environmental chemical exposure poses a risk to thyroid function and child neurodevelopment.
  • Interference with thyroid hormone action during critical developmental windows can have lasting consequences.
  • Further research is needed to understand and mitigate the effects of environmental chemicals on the thyroid system in children.