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Updated: Aug 10, 2026
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A Model for Perineural Invasion in Head and Neck Squamous Cell Carcinoma
Published on: January 5, 2017
Perineural spread of facial squamous cell carcinoma
J H Nogajski1, J Brewer, C E Storey
1Department of Neurology, Pacific Laboratory Medicine Services, Royal North Shore Hospital, Level 4, Suite 8, Westbourne Street, St. Leonards, Sydney, New South Wales 2065, Australia.
Abstract:
A 64 year old man presented with progressive impairment of right sided cranial nerves. Chronic immunosuppression for renal transplantation had resulted in multiple squamous cell carcinomata of the head and neck. Magnetic resonance imaging and subsequent right facial nerve biopsy confirmed perineural spread of a squamous cell carcinoma as the cause of the multiple cranial neuropathies.
