Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Diffusion tensor imaging and tractography of human brain development.

Pratik Mukherjee1, Robert C McKinstry

  • 1Neuroradiology Section, Department of Radiology, University of California at San Francisco, CA 94143-0628, USA. pratik@radiology.ucsf.edu

Neuroimaging Clinics of North America
|March 18, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Gray Matter Morphological Networks are Associated with Neurobiological Features, Cognitive Status and Clinical Recovery in Traumatic Brain Injury.

medRxiv : the preprint server for health sciences·2026
Same author

Inflammatory blood-based biomarkers to aid in the assessment and prognostication of traumatic brain injury: a TRACK-TBI study.

Journal of neuroinflammation·2026
Same author

Decompression with or without Duraplasty for Chiari I and Syringomyelia.

The New England journal of medicine·2026
Same author

Goal-Oriented Attentional Self-Regulation Training Improves Executive Function and Complex Attention in Veterans With mTBI-Randomized-Control Study.

Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists·2026
Same author

Longitudinal pain intensity and interference symptomatology in mild traumatic brain injury: a TRACK-TBI study.

Pain·2026
Same author

Neuroworsening from a normal Glasgow Coma Scale Motor Score in the emergency department is an early predictor of neurosurgical intervention, hospital outcomes, and longitudinal disability in traumatic brain injury: A TRACK-TBI Study.

Injury·2026

Diffusion tensor imaging (DTI) offers a noninvasive view of brain development, revealing microstructural changes and connectivity from infancy to adulthood. This technique aids in assessing brain maturation and diagnosing disorders.

Area of Science:

  • Neuroimaging
  • Developmental Neuroscience
  • Biomedical Engineering

Background:

  • Conventional MRI lacks sensitivity to early microstructural changes in the developing brain.
  • Diffusion Tensor Imaging (DTI) provides enhanced visualization of neural organization.
  • Understanding brain maturation is crucial for diagnosing neurodevelopmental disorders.

Purpose of the Study:

  • To review the applications of DTI and fiber tractography in studying human brain development.
  • To highlight DTI's role in visualizing early cerebral architecture and white matter development.
  • To explore DTI's potential in assessing abnormal brain maturation and connectivity.

Main Methods:

  • Diffusion Tensor Imaging (DTI) for microstructural analysis.
  • Quantitative measures like mean diffusivity and fractional anisotropy.

Related Experiment Videos

  • Three-dimensional fiber tractography for axonal connectivity mapping.

    • Main Results:

    • DTI enables visualization of cerebral laminar architecture and developing white matter.
    • Reproducible quantitative DTI measures reflect tissue properties and developmental milestones.
    • Fiber tractography reveals developing and aberrant axonal connectivity.

    Conclusions:

    • DTI provides novel insights into human brain maturation.
    • DTI and fiber tractography enhance the diagnostic evaluation of congenital, metabolic, and neurodevelopmental disorders.
    • DTI promises to improve the assessment of abnormal brain development.