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Murine Prostate Micro-dissection and Surgical Castration
Published on: May 11, 2016
Prostate cancer in Alaska Native men, 1969-2003
Orrenzo B Snyder1, Janet J Kelly, Anne P Lanier
1Alaska Native Medical Center, Department of Urology, Anchorage, Alaska 99508, USA. osnyder@gci.net
International Journal of Circumpolar Health
|March 21, 2006
Summary
Prostate cancer incidence in Alaska Native men is lower than in US Whites, but has increased over time. Rates vary among Alaska Native ethnic groups, with reasons yet undetermined.
Area of Science:
- Oncology
- Epidemiology
- Public Health
Background:
- Prostate cancer incidence varies significantly across US racial groups.
- Previous reviews indicated low prostate cancer rates in Alaska Natives compared to US Whites and Blacks.
- A detailed report on prostate cancer in Alaska Natives was previously unpublished.
Purpose of the Study:
- To determine the incidence of prostate cancer in Alaska Native men.
- To compare prostate cancer rates between Alaska Natives and US Whites.
- To identify temporal trends and ethnic variations in prostate cancer incidence among Alaska Natives.
Main Methods:
- Utilized data from the Alaska Native Tumor Registry (1969-2003).
- Calculated age-adjusted incidence rates for all Alaska Natives and specific ethnic groups (Aleut, Eskimo, Indian).
- Employed odds ratios for US White comparisons and Chi-square analysis for temporal trends.
Main Results:
- 332 Alaska Native men were diagnosed with prostate cancer between 1969-2003.
- The age-adjusted incidence rate increased from 45.5 (1969-1983) to 69.5 per 100,000 (1994-2003).
- Alaska Native rates remain lower than US White rates (169.5 per 100,000, 1994-2002); rates were highest in Indians and Aleuts, lowest in Eskimos.
Conclusions:
- Prostate cancer incidence in Alaska Native men is significantly lower than in the US White population.
- Distinct differences in prostate cancer rates exist among Alaska Native ethnic groups.
- The underlying reasons for these observed ethnic disparities remain undetermined.
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