Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Multidimensional computerized adaptive testing of the EORTC QLQ-C30: basic developments and evaluations.

Morten Aa Petersen1, Mogens Groenvold, Neil Aaronson

  • 1The Research Unit, Department of Palliative Medicine, Bispebjerg Hospital, DK-2400, Copenhagen, NV, Denmark. map01@bbh.hosp.dk

Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation
|March 21, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Stakeholder perspectives on potential open-label bias in patient-reported outcome results from cancer clinical trials: evidence from the IMPROvE project.

Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research·2026
Same author

Psychometric validation of the Angioedema Quality of Life Questionnaire (AE-QoL) for hereditary angioedema.

Journal of patient-reported outcomes·2026
Same author

The argument-based approach to validity: theory, assumptions, evidence, and consequences.

Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation·2026
Same author

Exploring health system factors related to the quality of life of people with (a history of) cancer: a rapid review.

Health and quality of life outcomes·2026
Same author

Health-related quality of life domains relevant to people in Europe undergoing cancer treatment: a systematic review of qualitative research.

Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation·2026
Same author

Prognostic value for overall survival of the EORTC QLQ-C30 Summary Score: An analysis of 5 closed EORTC trials.

European journal of cancer (Oxford, England : 1990)·2026
Same journal

Quality of life dynamics in the gastric cancer dyad: an actor-partner interdependence model analysis guiding the development of a family-centered nursing framework.

Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation·2026
Same journal

Correction: Self-stigma and suicide risk mediates the associations of inattention/impulsivity symptoms with psychological distress and quality of life among people with schizophrenia.

Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation·2026
Same journal

A methodological overview of new measure development for the Limb Injury Measurement Battery for Quality of Life (LIMB-QOL).

Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation·2026
Same journal

Overview of the limb injury measurement battery for quality of life (LIMB-QOL).

Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation·2026
Same journal

Agreement between the EQ-5D-5L anxiety/depression dimension and GAD-7/PHQ-9 for psychological distress assessment in patients with hematologic malignancies.

Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation·2026
Same journal

Empirical comparison of health-related quality of life and subjective well-being measures in Australian adolescents.

Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation·2026
See all related articles

Multidimensional computerized adaptive testing (CAT) efficiently measures health-related quality of life (HRQOL) domains. This approach offers high precision with fewer items, enhancing patient assessment.

Area of Science:

  • Health Outcomes Research
  • Psychometrics
  • Cancer Survivorship

Background:

  • Self-report questionnaires are standard for measuring health-related quality of life (HRQOL).
  • Computerized adaptive testing (CAT) offers personalized measurement but is typically unidimensional.
  • Correlations between HRQOL domains suggest potential for multidimensional approaches.

Purpose of the Study:

  • To investigate the advantages and challenges of multidimensional CAT for HRQOL measurement.
  • To evaluate the efficiency and precision of assessing multiple HRQOL domains simultaneously.
  • To explore the application of multidimensional CAT in cancer patient populations.

Main Methods:

  • Evaluated multidimensional CAT using three EORTC QLQ-C30 scales: physical functioning, emotional functioning, and fatigue.

Related Experiment Videos

  • Utilized a large database of 2958 European cancer patients for analysis.
  • Compared scores from multidimensional CAT with those from traditional, full-scale assessments.

    • Main Results:

    • Multidimensional CAT successfully obtained scores for physical functioning, emotional functioning, and fatigue.
    • Measurement precision was maintained with only five to seven items administered.
    • Results closely approximated scores derived from the full 12-item scales.

    Conclusions:

    • Multidimensional CAT shows significant potential to enhance measurement precision and efficiency in HRQOL assessment.
    • Further research is recommended, particularly on the underlying estimation models and conceptual frameworks for multidimensional CAT.
    • This approach may offer a more streamlined and accurate method for evaluating patient-reported outcomes.