Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Coronary artery bypass.

Ian Weir1

  • 1London Chest Hospital, Bonner Road, London E2 9JX, UK. ian.weir@bartsandthelondon.nhs.uk

Annals of the Royal College of Surgeons of England
|March 23, 2006
PubMed
Summary

Coronary artery bypass grafting (CABG) is successful, but off-pump CABG (OPCAB) aims to reduce risks. While OPCAB shows some benefits, concerns about revascularization completeness and anastomosis quality persist.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Sleep Medicine Milestones 2.0: designed for our field.

Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine·2020
Same author

ATS Core Curriculum 2015: Part II. Adult Sleep Medicine.

Annals of the American Thoracic Society·2015
Same author

Unusual mode of mechanical failure of an AO cannulated self drilling screw. A case report.

Acta orthopaedica Belgica·2009
Same author

Survival benefit of the full selective digestive decontamination regimen.

Journal of critical care·2009
Same author

Topical chlorhexidine and ventilator-associated pneumonia.

Critical care medicine·2007
Same author

Coronary artery stenosis.

Annals of the Royal College of Surgeons of England·2006

Area of Science:

  • Cardiovascular Surgery
  • Thoracic Surgery

Background:

  • Coronary artery bypass grafting (CABG) is a successful myocardial revascularization procedure, with over 25,000 UK cases annually and ~2% operative mortality.
  • Increased percutaneous coronary interventions have plateaued or decreased surgical revascularization rates.
  • Off-pump coronary artery bypass (OPCAB) surgery, performed without a heart-lung machine, has gained traction to reduce operative morbidity and mortality.

Purpose of the Study:

  • To evaluate the efficacy and safety of off-pump coronary artery bypass (OPCAB) surgery compared to conventional on-pump CABG.
  • To review the current literature and surgical approaches regarding OPCAB procedures.
  • To address concerns regarding revascularization completeness and anastomosis quality in OPCAB.

Main Methods:

  • Review of comparative literature on OPCAB versus conventional CABG.
  • Discussion of surgical techniques and technological advancements enabling OPCAB.
  • Presentation of arguments for and against OPCAB by leading surgical groups.

Main Results:

  • OPCAB surgery has seen a dramatic increase in use, driven by new stabilization devices.
  • Some reduction in morbidity has been demonstrated with OPCAB, but it has not been as significant as initially hoped.
  • Concerns persist regarding the completeness of revascularization and the quality of anastomoses, especially in less accessible coronary territories.

Conclusions:

  • While OPCAB aims to minimize risks associated with extracorporeal circulation, challenges in achieving complete revascularization and high-quality anastomoses remain.
  • Designing robust clinical trials to compare OPCAB and conventional CABG is difficult due to small outcome differences.
  • Further research and technological advancements are needed to optimize OPCAB outcomes and fully establish its benefits.

Related Experiment Videos