Related Experiment Video
Updated: Aug 9, 2026

Non-Invasive Visualization of Nailbed Microvascular Morphology in Mice Using Capillaroscopy
Published on: February 28, 2025
[Suspicion of systemic diseases through nails abnormalities]
Paulina Silva1, Cristián Vera, Marianne Kolbach
1Unidad Docente Asociada de Dermatología, Facultad de Medicina, Pontificia Universidad Católica de Chile, Chile.
Nail abnormalities can indicate underlying health issues, ranging from common problems to serious systemic diseases. Recognizing these changes is crucial for early detection and diagnosis of various medical conditions.
Area of Science:
- Dermatology and Systemic Disease Manifestations
Context:
- Fingernails and toenails serve as protective coverings.
- Nail appearance can be altered by genetic factors, trauma, lifestyle, and infections.
Purpose:
- To highlight the diagnostic significance of nail abnormalities.
- To correlate nail changes with potential systemic diseases.
Summary:
- Nail structure and appearance are detailed.
- Various factors influencing nail health are identified, including inheritance, injury, habits, cosmetics, and infections.
- The link between nail variations and systemic health conditions is emphasized.
Impact:
- Increased awareness of nail changes can aid in the early identification of systemic diseases.
- Understanding normal nail variants and their abnormalities improves diagnostic capabilities.
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