Related Experiment Video
Updated: Aug 9, 2026

Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations
Published on: October 20, 2017
Fatal giant pediatric intracranial cavernous angioma
Funda Corapçioğlu1, Gür Akansel, Erdem Gönüllü
1Department of Pediatrics, Kocaeli University Faculty of Medicine, Kocaeli, Turkey.
Insights
A rare pediatric brain tumor, cavernous angioma, can cause sudden, fatal hemorrhage. Early detection via imaging and prompt surgical removal are crucial for better outcomes in children.
Area of Science:
- Neurology
- Pediatric Neurosurgery
- Vascular Malformations
Background:
- Cavernous angiomas are benign vascular lesions in the central nervous system.
- Symptoms often arise from acute hemorrhage, causing increased intracranial pressure or altered consciousness.
Observation:
- A previously healthy four-year-old girl presented with sudden loss of consciousness, vomiting, and seizures.
- CT revealed a large, hyperdense intraaxial lesion in the left frontoparietal region with surrounding edema and ventricular compression.
- Despite surgical excision, the patient's Glasgow Coma Score (GCS) did not improve, leading to a diagnosis of brain death.
Findings:
- Pathologic examination confirmed the lesion as a cavernous hemangioma.
- This case highlights the potential for rapid and fatal hemorrhage from cavernous angiomas in pediatric patients.
Implications:
- Cavernous angiomas in children can have a devastatingly rapid clinical course.
- Early diagnosis using CT or MRI and prompt surgical intervention are essential for potentially improving outcomes.
Abstract:
Cavernous angioma is a benign vascular lesion that may occur in the central nervous system. The symptoms of raised intracranial pressure or consciousness alteration are usually related to acute hemorrhage. A previously healthy four-year-old girl was admitted with sudden loss of consciousness, vomiting and clonic seizures. Her Glasgow coma score (GCS) was 7 at presentation (5 m 1v 1e). Anisocoria and mydriasis were present on the right. Computerized tomography revealed a giant spherical, hyperdense intraaxial left frontoparietal lesion. The findings of surrounding vasogenic edema and compression of the adjacent lateral ventricle were seen on computerized tomography (CT). She was taken to operation and the mass was grossly excised. The GCS remained unchanged. A diagnosis of brain death was made. A cavernous hemangioma was diagnosed with pathologic examination. In conclusion, a cavernous angioma may occasionally follow a rapid and fatal course by causing gross hemorrhage in the pediatric age group. Early recognition by CT or magnetic resonance imaging (MRI) and prompt surgical evacuation are necessary.
Related Concept Videos
Increased Intracranial Pressure l: Introduction
Cerebral Edema ll: Pathophysiology
