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Updated: Jun 24, 2026

Ex vivo Method for High Resolution Imaging of Cilia Motility in Rodent Airway Epithelia
Published on: August 8, 2013
Novel tools to unravel molecular mechanisms in cilia-related disorders
Manfred Fliegauf1, Heymut Omran
1Department of Pediatrics and Adolescent Medicine, University Hospital Freiburg, Mathildenstrasse 1, 79106 Freiburg, Germany.
Abstract:
Cilia are hair-like organelles extending from the cell surface that execute motile (e.g. respiratory cilia) and/or sensory functions (e.g. renal monocilia). The basic ultrastructure of cilia and flagella has been well established by electron microscopy. Several recent reports have now provided intriguing new insights into the complex molecular composition of cilia and flagella. These data from genome, proteome and transcriptome analyses will facilitate the systematic discovery and understanding of genes responsible for human cilia-related diseases, such as primary ciliary dyskinesia, polycystic kidney disease and male sterility.
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