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Thallium toxicosis in a Pit Bull Terrier
Petra A Volmer1, Valentina Merola, Tanasa Osborne
1University of Illinois, Veterinary Diagnostic Laboratory, Urbana 61802, USA.
Summary
Thallium toxicosis in a Pit Bull Terrier caused severe gastrointestinal and neurological signs, leading to death. This case highlights the importance of considering thallium poisoning in animals with unexplained symptoms.
Area of Science:
- Veterinary Toxicology
- Animal Pathology
Background:
- Thallium sulfate, a potent neurotoxin, is rarely encountered in veterinary medicine.
- Intentional poisoning of animals with heavy metals presents a diagnostic challenge.
Observation:
- An adult Pit Bull Terrier presented with anorexia, emesis, weakness, proprioceptive deficits, and hemorrhagic diarrhea.
- Histological examination revealed severe necrotizing enterocolitis and pulmonary edema.
Findings:
- High concentrations of thallium were detected in the dog's liver (18 ppm) and kidneys (26 ppm).
- The thallium source was identified as thallium sulfate, intentionally administered.
Implications:
- This case underscores the need to include thallium toxicosis in the differential diagnosis for animals with complex gastrointestinal and neurological signs.
- Despite limited production, thallium remains a potential environmental and intentional toxin for companion animals.

