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Updated: Jul 30, 2026

Tumor Treating Field Therapy in Combination with Bevacizumab for the Treatment of Recurrent Glioblastoma
Published on: October 27, 2014
[Tumor necrosis factor blocking agents: a review. Part II: safety and recommendations]
C Rodríguez Moreno1, P López Vázquez, C Durán Parrondo
1Servicio de Farmacología Clínica, Complexo Hospitalario Universitario, Santiago de Compostela, A Coruña. carlos.rodriguez.moreno@sergas.es
Abstract:
Blockade of tumor necrosis factor with monoclonal antibodies, has emerged as one of the most promising therapies in some autoimmune conditions as rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis and Crohn's disease. They have shown effectiveness on reducing symptoms and modifying the progression of the disease. However, they disrupt the balance of inflammatory and immune responses and some risks associated with TNF-blockers have become apparent. The purpose of this article is to review the evidence about benefits and risk associated with the use of TNF-blockers in approved indications and to provide practical recommendations for its use in the management of this conditions.
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