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Related Experiment Videos

Childhood primary mesenteric seminoma.

Sameer Bakhshi1, Devinder Singh, A K Karak

  • 1Department of Medical Oncology, Dr. B. R. A. Institute Rotary Cancer Hospital, New Delhi, India. sambakh@hotmail.com

Indian Journal of Pediatrics
|March 29, 2006
PubMed
Summary
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An 11-year-old boy with a mesenteric seminoma, a rare extragonadal germ cell tumor, achieved a complete remission after chemotherapy. The patient remains disease-free for two years, highlighting successful treatment outcomes.

Area of Science:

  • Pediatric Oncology
  • Surgical Pathology
  • Medical Oncology

Background:

  • Extragonadal germ cell tumors (EGCTs) are rare, with primary mesenteric seminoma being an uncommon subtype.
  • Mesenteric tumors in children can present insidiously with non-specific symptoms like abdominal masses.

Observation:

  • An 11-year-old presented with an abdominal lump, diagnosed as a primary extragonadal mesenteric seminoma.
  • The tumor's location within the mesentery posed unique diagnostic and surgical challenges.

Findings:

  • The patient received four cycles of combination chemotherapy, including cisplatin, etoposide, and bleomycin (BEP regimen).
  • Post-treatment surveillance confirmed the patient to be disease-free for two years, indicating a favorable response.

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Implications:

  • This case highlights the efficacy of platinum-based chemotherapy in treating extragonadal mesenteric seminomas in pediatric patients.
  • Successful management underscores the importance of multidisciplinary approaches for rare pediatric malignancies.