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Updated: Aug 9, 2026

Antigenic Liposomes for Generation of Disease-specific Antibodies
Published on: October 25, 2018
Do antiphospholipid antibodies develop for a purpose?
1Department of Clinical Pharmacology, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA. jtmmail@aol.com
Abstract:
There is a growing body of literature suggesting that antiphospholipid antibodies develop for a purpose, that they play several key roles in the innate immune response, and are only rendered pathologic in susceptible people under adverse intravascular conditions. This paper will review evidence that the autoantibodies associated with the antiphospholipid syndrome develop from natural autoantibodies for purposes that are beneficial to host defense, and are only rendered pathologic as a result of adverse intravascular events.
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