Related Experiment Video
Updated: May 11, 2026
12:04
The bm12 Inducible Model of Systemic Lupus Erythematosus (SLE) in C57BL/6 Mice
Published on: November 1, 2015
Perioperative Management Considerations for Patients with Systemic Lupus Erythematosus.
Sofia Flouda1, Romy Kallas2, Kyriakos A Kirou3,4
1Rheumatology and Immunology Department, 4th Department of Internal Medicine, Attikon University Hospital, NKUA, Athens, Greece.
Current Rheumatology Reports
|May 9, 2026
Summary
Systemic lupus erythematosus (SLE) patients face higher surgical risks, including infections and bleeding. Optimizing perioperative care by managing disease activity and medications is crucial for better surgical outcomes in SLE patients.
Area of Science:
- Rheumatology
- Surgical Outcomes
- Immunology
Background:
- Systemic lupus erythematosus (SLE) involves multisystem organ damage.
- SLE patients often require surgery due to disease complications.
- Perioperative management for SLE patients presents unique challenges.
Purpose of the Study:
- To review surgical outcomes in SLE patients.
- To identify strategies for optimizing perioperative care in SLE.
- To highlight recent guidelines for managing SLE during surgery.
Main Methods:
- Review of existing literature on surgical outcomes in SLE.
- Analysis of factors influencing postoperative complications.
- Examination of current guidelines for perioperative management.
Main Results:
- SLE patients have increased risks of postoperative infections, thrombosis, and hemorrhage.
- Lupus activity, disease severity, comorbidities, and glucocorticoid use predict poor outcomes.
- Recent guidelines recommend achieving low disease activity and adjusting immunosuppressive therapies (IST) perioperatively.
Conclusions:
- Multidisciplinary planning and careful management of GC and IST are essential.
- Optimizing perioperative strategies can improve surgical outcomes for SLE patients.
- Further prospective studies are needed to advance perioperative care for SLE.
Keywords:
GlucocorticoidsImmunosuppressive therapiesOutcomesPerioperative managementSystemic Lupus Erythematosus (SLE)More Related Videos
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