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In Vitro Evaluation of The Effects Of Er,Cr:YSGG and Diode Lasers Used on Titanium Cylinder
Published on: June 6, 2025
Improving the initial biocompatibility of a titanium surface using an Er,Cr:YSGG laser-powered hydrokinetic system
Her-Hsiung Huang1, Yu-Chiao Chuang, Zhi-Hwa Chen
1Faculty of Dentistry, School of Dentistry, National Yang-Ming University, Taipei 112, Taiwan.
Summary
Improving titanium biocompatibility with Er,Cr:YSGG laser treatment enhances initial cell proliferation and spreading. This laser-powered hydrokinetic system offers a promising method for better titanium surface integration in biomedical applications.
Area of Science:
- Biomaterials Science
- Surface Engineering
- Cell Biology
Background:
- Titanium (Ti) is widely used in biomedical implants due to its excellent mechanical properties.
- Enhancing the initial biocompatibility of titanium surfaces is crucial for successful osseointegration and implant longevity.
- Current surface modification techniques aim to improve cell attachment and proliferation on titanium substrates.
Purpose of the Study:
- To investigate the efficacy of an Er,Cr:YSGG laser-powered hydrokinetic system in enhancing the initial biocompatibility of titanium.
- To evaluate the effect of different laser energy densities on cell proliferation and surface morphology of titanium.
- To determine if laser treatment improves initial cell attachment and spreading on titanium surfaces.
Main Methods:
- Titanium substrates were treated using an Er,Cr:YSGG laser-powered hydrokinetic system at energy densities of 125 and 190 J/cm(2).
- Human osteosarcoma U2-OS cells were cultured on treated and untreated titanium substrates for 1 and 3 days.
- Initial cell proliferation index (CPI) was calculated, and cell spreading morphology was assessed using field-emission scanning electron microscopy.
Main Results:
- Er,Cr:YSGG laser-treated titanium exhibited a 1.2-1.3 times higher initial CPI compared to untreated titanium (P<0.001).
- Laser treatment significantly improved the cell spreading morphology on the titanium surface.
- Higher laser energy density (190 J/cm(2)) did not yield significantly better results than the lower energy density (125 J/cm(2)).
Conclusions:
- The Er,Cr:YSGG laser-powered hydrokinetic system effectively improves the initial biocompatibility of titanium surfaces.
- This laser-based approach enhances initial cell proliferation and promotes better cell morphology on titanium.
- The findings suggest a viable method for optimizing titanium implant surfaces for improved biological response.