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Updated: Aug 9, 2026

Tachycardia-Induced Cardiomyopathy As a Chronic Heart Failure Model in Swine
Published on: February 17, 2018
[Persistent left ventricular systolic dysfunction in a patient with ampulla cardiomyopathy: a case report]
Tomoyuki Watanabe1, Masumi Iwai-Takano, Shinichi Satoh
1Division of Cardiology, Health Co-op, Watari Hospital, Nakae-cho 34, Watari, Fukushima, Fukushima 960 8141. t-watana@fmc.u-coop.or.jp
Ampulla cardiomyopathy, a form of heart failure, can cause chest pain and ST elevation without blocked arteries. Microvascular dysfunction may underlie this condition, impacting heart muscle function.
Area of Science:
- Cardiology
- Cardiovascular Medicine
- Heart Failure Research
Background:
- Diastolic heart failure management
- Acute coronary syndrome presentation
- Cardiomyopathy diagnosis
Observation:
- An 81-year-old woman presented with diastolic heart failure, later experiencing unexplained chest pain and ST elevation.
- Coronary angiography revealed no significant epicardial stenosis, but left ventriculography showed apical akinesis.
- Diagnosis of ampulla cardiomyopathy was made, with persistent apical akinesis and evidence of microvascular dysfunction for one year.
Findings:
- Ampulla cardiomyopathy can mimic acute myocardial infarction without obstructive coronary artery disease.
- Persistent apical akinesis and microvascular dysfunction were observed for one year post-diagnosis.
- Electrocardiographic abnormalities normalized within two months.
Implications:
- Microvascular dysfunction is a potential key factor in the pathophysiology of ampulla cardiomyopathy.
- This case highlights the importance of considering non-obstructive causes of myocardial dysfunction.
- Further research into microvascular mechanisms in cardiomyopathies is warranted.
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