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Updated: Aug 9, 2026
Inspiratory Muscle Training as an Adjunct to the Treatment of Weaning Failure in Critically Ill Patients: A Practical Guide
Published on: January 30, 2026
Expiratory muscle strength training in persons with multiple sclerosis having mild to moderate disability: effect on
Toni Chiara1, A Daniel Martin, Paul W Davenport
1Brain Rehabilitation Research Center, Malcom Randall VA Medical Center, Gainesville, FL 32608, USA. toni.chiara@med.va.gov
Objective:
To determine the effect of expiratory muscle strength training (EMST) on maximal expiratory strength, pulmonary function, and maximal voluntary cough in persons with multiple sclerosis (MS) having mild to moderate disability.
Design:
Before-after trial.
Setting:
Assessments were completed in the privacy of the subject's home or exercise physiology laboratory.
Participants:
Seventeen persons with MS were age- and sex-matched to 14 healthy controls.
Intervention:
Eight weeks of EMST and 4 weeks of detraining.
Main Outcome Measures:
Maximal respiratory pressures, pulmonary function, and maximal voluntary cough were assessed 3 times (pretraining, posttraining, detraining). Maximal expiratory pressure (MEP) was assessed weekly and training intensity adjusted based on the new measurement.
Results:
Subjects with MS had lower MEP, decreased pulmonary function, and weaker maximal voluntary cough at each assessment. EMST increased MEP and peak expiratory flow. However, improvement in maximal voluntary cough only occurred in subjects with a moderate level of disability when the MS group was subdivided into mild and moderate disability levels based on the Expanded Disability Status Scale.
Conclusions:
EMST is a viable tool to enhance the strength of the respiratory muscles. However, further work is needed to determine the best parameters to assess change in cough following EMST.
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