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[The anti-inflammation effects of Smilax china ethylacetate extract in rats and mice]
Xiao-Shuni Shu1, Zhong-Hong Gao, Xiang-Liang Yang
1Department of Biology & Foodstuff Engineering, Changsha University of Science & Technology, Changsha 410076, China. sxs732@yahoo.com.cn
Objective:
To study the anti-inflammations of the ethyl acetate extract of S. china on acute and chronic inflammations.
Method:
The rat paw edema induced by egg-albumin, the ear edema and the foot edema of mice induced by xylene and formaldehyde, the increased vascular permeability of capillary induced by intraperitoneal injection of 0.7% acetic acid in mice were used to study on the acute, early inflammations and chronic inflammation for the ethyl acetate extract of S. china.
Result:
The extract (50-100 g x kg(-1)) could significantly decrease the rat paw edema, and inhibit the ear edema, the increased vascular permeability and the foot edema of mice.
Conclusion:
The ethyl acetate extract of S. china possesses remarkable anti-inflammatory effects on acute inflammation, and also displays anti-inflammatory effects on the chronic inflammation at a certain extent.