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[Castleman's disease: 6 cases report]
Insights
This study details six Castleman
Area of Science:
- Oncology
- Pathology
- Radiology
Background:
- Castleman's disease is a rare lymphoproliferative disorder.
- It can manifest in various locations, posing diagnostic challenges.
Observation:
- Six diverse cases of Castleman's disease were analyzed.
- Locations included lung, mediastinum, gallbladder fossa, perinephric space, and mesentery.
- Imaging characteristics varied based on histological subtype.
Findings:
- Hyaline-vascular Castleman's disease demonstrated significant contrast enhancement.
- The plasma cell variant showed minimal enhancement after contrast administration.
- Abdominal ultrasound revealed a homogeneous, hypoechoic pattern in one case.
Implications:
- Understanding imaging features aids in diagnosing Castleman's disease.
- Contrast enhancement patterns can help differentiate subtypes.
- Multifocal presentation requires comprehensive evaluation.
Abstract:
The authors present six cases of Castleman's disease. One was located in the left middle lung near the lung root, one in the right posterior mediastinum, one in the gallbladder fossa, one in the left perinephric space, and the last two in the mesenteric region. All the hyaline-vascular type showed good enhancement after contrast medium injection. The only one case of plasma cell type located in mesentery was not enhanced after contrast injection. Ultrasound of abdomen was performed in one of the six patients, which showed homogeneous and hypoechoic in echo-pattern.