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Related Experiment Videos

Hyperintense cirrhotic nodules on MRI.

S A Koslow1, P L Davis, G B DeMarino

  • 1Department of Radiology, Presbyterian-University Hospital, University of Pittsburgh, Pennsylvania 15213.

Gastrointestinal Radiology
|January 1, 1991
PubMed
Summary

Regenerating nodules in cirrhosis can appear differently on MRI scans. This study found that these nodules may show a more variable appearance on short TR/TE images than previously thought.

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Area of Science:

  • Radiology
  • Hepatology
  • Medical Imaging

Background:

  • Cirrhosis is characterized by regenerating nodules.
  • These nodules are typically isointense to liver parenchyma on MRI.
  • Occasionally, iron deposition causes hypointensity in nodules on all MRI sequences.

Purpose of the Study:

  • To investigate the variable appearance of regenerating nodules in cirrhosis on MRI.
  • To assess the signal intensity characteristics of nodules across different MRI sequences.

Main Methods:

  • Retrospective review of 21 cases with pathologically proven cirrhosis.
  • Analysis of MRI scans, focusing on signal intensity of nodules relative to liver parenchyma.
  • Evaluation across various sequences including short TR/TE, long TR/TE, and GRASS.

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Main Results:

  • Five patients showed nodules hyperintense on short TR/TE images, becoming isointense on long TR/TE or GRASS.
  • Five patients had nodules hypointense on long TR/TE or GRASS images.
  • One of these patients also exhibited hypointense nodules on short TR/TE images.

Conclusions:

  • Regenerating nodules in cirrhosis demonstrate a variable appearance on MRI.
  • Short TR/TE sequences may show more diverse signal intensities for these nodules than previously recognized.