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The Scientific Misconduct Questionnaire--Revised (SMQ-R): validation and psychometric testing.

Marion E Broome1, Erica Pryor, Barbara Habermann

  • 1School of Nursing, Indiana University, 1111 Middle Dr. NU 132, Indianapolis, IN 46202, USA. mbroome@iupui.edu

Accountability in Research
|April 4, 2006
PubMed
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The Scientific Misconduct Questionnaire-Revised (SMQ-R) was developed to assess research coordinators' perceptions of scientific misconduct in clinical trials. Psychometric analyses indicate good internal consistency and construct validity, supporting its use in research settings.

Area of Science:

  • * Clinical Research Management
  • * Research Ethics and Integrity

Background:

  • * Scientific misconduct poses a significant threat to the integrity of research.
  • * Accurate measurement of perceptions regarding scientific misconduct is crucial for developing effective prevention strategies.

Purpose of the Study:

  • * To develop and validate the Scientific Misconduct Questionnaire-Revised (SMQ-R) for assessing research coordinators' perceptions of scientific misconduct.
  • * To provide psychometric evidence for the reliability and validity of the SMQ-R.

Main Methods:

  • * Development of the SMQ-R involved literature review, expert panel input, and item generation, resulting in a 68-item closed-choice and 12-item open-ended questionnaire.
  • * The SMQ-R was administered to a national sample of 5302 research coordinators.
Keywords:
Biomedical and Behavioral ResearchEmpirical Approach

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  • * Psychometric properties were evaluated using Cronbach's alpha for internal consistency and confirmatory factor analysis for construct validity.

    • Main Results:

    • * The SMQ-R demonstrated good internal consistency, with Cronbach's alpha values ranging from .83 to .84 for subscales.
    • * Confirmatory factor analysis supported the construct validity of the instrument, identifying five distinct factors within three subscales.
    • * The known groups approach further corroborated the construct validity of the SMQ-R.

    Conclusions:

    • * The SMQ-R is a useful instrument for gathering data on research coordinators' perceptions of scientific misconduct prevalence and influencing factors.
    • * The psychometric evaluation indicates adequate construct validity and good internal consistency for the SMQ-R.
    • * Further refinement of the SMQ-R is recommended for future research endeavors.