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Effects of coronary revascularization and concomitant aneurysmectomy on QT interval duration and dispersion

Feridun Kosar1, Vedat Nisanoglu, Yuksel Aksoy

  • 1Department of Cardiology, Faculty of Medicine, Inonu University, Turgut Ozal Medical Center, Malatya 44069, Turkey. mferidunkosar@yahoo.com

Journal of Electrocardiology
|April 4, 2006
PubMed

Insights

Coronary artery bypass grafting (CABG) combined with left ventricular aneurysmectomy significantly reduces QT dispersion (QTd) and corrected QT intervals (QTc) in patients with coronary artery disease and left ventricular aneurysm (LVA). This combined surgical approach offers beneficial cardiac electrophysiological effects.

Area of Science:

  • Cardiology
  • Cardiac Surgery
  • Electrophysiology

Background:

  • Reduced QT dispersion (QTd) observed with thrombolytics and CABG.
  • Left ventricular aneurysm (LVA) in patients with coronary artery disease (CAD) presents unique challenges.

Purpose of the Study:

  • Investigate changes in corrected QT intervals and QT dispersion after CABG with concomitant aneurysmectomy.
  • Evaluate the impact of combined surgical intervention on cardiac electrophysiology in LVA patients.

Main Methods:

  • Study included 43 patients with CAD and LVA, and 32 controls with CAD without LVA.
  • Patients underwent CABG and aneurysmectomy in the same session.
  • Measured corrected maximum and minimum QT interval (QTcmax, QTcmin) and QT dispersion (QTcd) pre- and post-surgery.

Main Results:

  • Patients with LVA had significantly higher QTcmax and QTcd compared to controls (P < .001).
  • Significant reduction in QTcmax and QTcd observed post-surgery in LVA patients (P < .001).

Conclusions:

  • CABG and concomitant aneurysmectomy significantly reduce QTcmax and QTcd.
  • Combined coronary revascularization and left ventricular reconstruction yield beneficial effects on QT interval duration and dispersion.

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