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Updated: Aug 18, 2026

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Biological Compatibility Profile on Biomaterials for Bone Regeneration
Published on: November 16, 2018
Alveolar ridge augmentation with hydroxylapatite using fibrin sealant for fixation. Part II: Clinical application
1Department of Maxillofacial Surgery, University of Heidelberg, Germany.
International Journal of Oral and Maxillofacial Surgery
|August 1, 1991
Abstract:
The use of fibrin as a resorbable biological adhesive permits moulding of HA granules into individually shaped implants. The binder prevents dislocation of granules during delivery, and the moulded implants securely retain their shape until fibrous tissue ingrowth is complete. Three years of clinical experience have shown that, mouldable fibrin-bound HA has so far proved suitable as a bone substitute in preprosthetic as well as in plastic and reconstructive surgery.

