Related Experiment Video
Updated: Aug 9, 2026

Transplantation of Bioengineered Lung Using Decellularized Mouse Lungs and Primary Human Endothelial Cells
Published on: March 28, 2025
[The cardiac lung]
Laurence Gabriel1, Luc Delaunois
1Université catholique de Louvain, cliniques universitaires de Mont-Godinne, B-5530 Yvoir, Belgique.
Abstract:
Since lungs, great vessels and heart share together the main volume of the thorax, itself limited by the thoracic wall, variations in pressure or volume of each one must influence the work of the others especially in case of disease. Failure of the left heart overloads the pulmonary vascular bed, induces an interstitial oedema followed by an alveolar oedema with mostly restrictive functional consequences on the lung and disturbed gas exchange. Heart failure can be due to systolic or diastolic dysfunction. These consequences of myocardial and valve diseases of the left heart are initially revealed by unusual dyspnea during exercise worsening progressively to symptoms at rest and even during sleep. Informations obtained from history, physical examination, biology, radiography and echocardiography imaging procedures, respiratory function tests and polysomnography help to precise the diagnosis and the prognosis. The treatment of this cardiac lung conditions depends on its precise etiology.
Related Concept Videos
Gross Anatomy of the Lungs
Overview of the Heart
The heart's structure...
Pulmonary Edema II: Pathophysiology
Anatomy of Respiratory System II: Lower Respiratory Tract
The Larynx
It is located between the pharynx and the trachea, acts as a passageway for air, and hosts several critical structures, such as the epiglottis, vocal cords, and glottis. The epiglottis acts as a gateway, guiding food to the...
Overview of Pulmonary Circulation
The process begins with the right ventricle of the heart pumping deoxygenated blood into the pulmonary trunk. This large vessel extends about 5 centimeters before splitting into the left and right pulmonary arteries. These arteries...
Cardiopulmonary Resuscitation I: Adult
