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Spontaneous Formation and Rearrangement of Artificial Lipid Nanotube Networks as a Bottom-Up Model for Endoplasmic Reticulum
Published on: January 22, 2019
Adsorption and spontaneous rupture of vesicles composed of two types of lipids
Vladimir P Zhdanov1, Kristian Dimitrievski, Bengt Kasemo
1Department of Applied Physics, Chalmers University of Technology, S-412 96 Göteborg, Sweden. zhdanov@catalysis.nsk.su
Abstract:
To analyze the adsorption of single vesicles composed of two types of lipids (e.g., zwitterionic and positively charged lipids or zwitterionic and negatively charged lipids), we propose a statistical model taking into account lipid-surface interactions, lipid-lipid lateral interactions, and vesicle bending energy. Our treatment specifies how these parameters govern vesicle adsorption, shows how the radius of the vesicle-surface contact area may depend on the vesicle composition, and clarifies the conditions for vesicle rupture.
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