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Updated: Jul 21, 2026

Analysis of Translation Initiation During Stress Conditions by Polysome Profiling
Published on: May 19, 2014
Challenges and strategies of instrument translation
Wen-Ling Wang1, Hwei-Ling Lee, Susan Jane Fetzer
1National Cheng Kung University, Tainan, Taiwan.
Abstract:
The often-cited back translation procedure used for the translation of research instruments has not been consistently described in cross-cultural literature. Translation errors resulting in conceptually dissimilar instruments can compromise comparisons of cross-cultural health initiatives. This report describes a five-step translation procedure and equivalence and reliability testing process used to develop the High School Questionnaire: Profile of Experiences (HSQ) in Mandarin. Each step of the translation process provided additional information and detected discrepancies between the English and Mandarin versions of the HSQ. Issues related to grammatical translation, cultural usage and experience, syntax, and concept interpretation were exposed by the translation process. The procedures used in this 18-month study were rigorous enough to create an instrument that was both linguistically appropriate and culturally relevant.
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Translation
Translation is the process of synthesizing proteins from the genetic information carried by messenger RNA (mRNA). Following transcription, it constitutes the final step in the expression of genes. This process is carried out by ribosomes, complexes of protein and specialized RNA molecules. Ribosomes, transfer RNA (tRNA), and other proteins produce a chain of amino acids—the polypeptide—as the end product of translation.
Translation Produces the Building Blocks of Life
Translation
Translation is the process of synthesizing proteins from the genetic information carried by messenger RNA (mRNA). Following transcription, it constitutes the final step in the expression of genes. This process is carried out by ribosomes, complexes of protein and specialized RNA molecules. Ribosomes, transfer RNA (tRNA), and other proteins produce a chain of amino acids—the polypeptide—as the end product of translation.
Translation Produces the Building Blocks of Life
Improving Translational Accuracy
Translation
Translation is the process of synthesizing proteins from the genetic information carried by messenger RNA (mRNA). Following transcription, it constitutes the final step in the expression of genes. This process is carried out by ribosomes, complexes of protein and specialized RNA molecules. Ribosomes, transfer RNA (tRNA), and other proteins produce a chain of amino acids—the polypeptide—as the end product of translation.
Translation Produces the Building Blocks of Life
Improving Translational Accuracy
Translation
Translation Produces the Building Blocks of Life
Proteins are called the...

