Rectal gonorrhoea in men -- is microscopy still a useful tool?
D Grover1, K P Prime, M V Prince
1Department of Genito-Urinary Medicine, Mortimer Market Centre, Camden PCT, London WC1E 6AU, UK. deepa.grover@camdenpct.nhs.uk
International Journal of STD & AIDS
|April 6, 2006
Summary
Rectal microscopy for gonorrhoea (GC) in men aids immediate diagnosis. This method increased the number of men treated for rectal GC during their initial clinic visit, improving timely management.
Area of Science:
- Microbiology
- Sexual Health
- Public Health
Background:
- Rectal gonorrhoea (GC) diagnosis is challenging due to poor symptom correlation.
- Current gold standard, Neisseria gonorrhoeae culture, provides delayed results.
- Gram staining offers high specificity but low sensitivity for rectal GC.
Purpose of the Study:
- To audit the impact of rectal microscopy on diagnosing and treating rectal GC at initial presentation.
- To assess if rectal microscopy increases the proportion of men treated for rectal GC during their first visit.
Main Methods:
- A 12-month audit at an inner London genitourinary clinic.
- Review of 136 episodes of rectal GC in 132 men.
- Analysis of rectal microscopy results and treatment initiation.
Main Results:
- Rectal microscopy was performed in 134 of 136 cases (98.5%).
- 35% (47/134) of rectal smears were positive for GC.
- 27% (24/90) of treated patients would have delayed treatment without microscopy.
Conclusions:
- Rectal microscopy is a valuable tool for the rapid diagnosis of rectal gonorrhoea.
- Implementing rectal microscopy increases the number of men treated for GC at their first attendance.
- This diagnostic approach improves timely management of rectal gonorrhoea in men.
Related Concept Videos
Trichomoniasis
Trichomonas vaginalis is a flagellated protozoan parasite and the causative agent of trichomoniasis, one of the most prevalent non-viral sexually transmitted infections in the United States. This extracellular parasite primarily colonizes the lower genitourinary tract in women—particularly the vagina—and in men, the urethra and prostate. Its structural and functional adaptations enable its survival, motility, and pathogenicity within the host environment.Structural Features and Host EntryT.
Amebiasis
Entamoeba histolytica, a protozoan parasite, is responsible for intestinal and extraintestinal amebiasis. Though a significant proportion of infections remain asymptomatic, approximately 50 million individuals annually are estimated to present with clinical disease, resulting in up to 100,000 deaths globally. The disease burden is disproportionately high in regions with lower socioeconomic status, such as parts of India, Africa, Mexico, and Latin America.Etiology and TransmissionThe infective...
Rapid Identification of Pathogens
MALDI-TOF MS has transformed clinical microbiology by offering a rapid and reliable method for pathogen identification. The traditional approach to microbial identification typically involves time-consuming culture techniques and biochemical tests, which can delay the initiation of appropriate antimicrobial therapy. MALDI-TOF MS avoids these delays by using characteristic ribosomal protein mass patterns of microbial cells, enabling accurate species-level identification within minutes.Principle...
Two-Dimensional Microscopy in Microbiology
Two-dimensional (2D) microscopy encompasses a range of optical techniques that capture images within a single focal plane, offering detailed representations of microscopic structures. These techniques are essential in biological and medical research, enabling the visualization of cellular and subcellular structures with different levels of contrast and specificity.There are several major types of 2D microscopy, each with strengths and applications.Bright-Field MicroscopyBright-field microscopy...
Special Staining Techniques
Specialized staining techniques play a vital role in microbiology by enabling the visualization of specific bacterial structures that remain undetectable with standard microscopy methods. These techniques not only enhance the structural visualization of bacterial cells but also provide critical insights into their pathogenicity and classification. Additionally, they support diagnostic and research endeavors in microbiology by identifying key bacterial features.Capsule Staining for Virulence...

