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Updated: Aug 9, 2026

Microfluidic Co-culture of Renal Healthy and Tumor Epithelium to Model Kidney Cancer Progression
Published on: January 31, 2025
Mixed epithelial and stromal tumor of the kidney
Hsin-Pei Chou1, Yen-Chuan Ou, Chcn-Li Cheng
1Division of Urology, Department of Surgery, Taichung Veterans General Hospital, National Yang-Ming University School of Medicine, Taiwan, ROC.
Abstract:
A 42-year-old female presented with intermittent left flank pain for 2 years. She developed gross hematuria 1 month prior to seeking help. Intravenous pyelography showed filling defects within the lower portion of the left collecting system and renal pelvis causing hydronephrosis. Abdominal computed tomography revealed a huge cystic heterogenic tumor about 20 cm in largest diameter occupying the entire left kidney. A left radical nephrectomy was performed without complications. The pathology report confirmed the diagnosis of mixed epithelial and stromal tumor of the kidney. From pathologic survey, the spindle cells of this tumor were positive for muscle markers and expressed estrogen and/or progesterone receptors. We suggest that a mixed epithelial and stromal tumor of the kidney should be considered in all cystic renal tumors presenting in perimenopausal women.
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