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Site-specific recombination and shuffling of resistance genes in transposon Tn21
1Dpto. Biologia Molecular, University of Cantabria, Santander, Spain.
Research in Microbiology
|July 1, 1991
Abstract:
Many multidrug-resistant transposons found in natural isolates of Gram-negative bacteria are close relatives of Tn21. Thus, the Tn21 subgroup of the Tn3 family of transposable elements is the most successful homogeneous group in acquiring resistance to newly introduced antibiotics. This paper summarizes the mode of acquisition of resistance genes by these elements.