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The effect of hyperbaric oxygen on intraocular pressure
1Department of Opthalmology, GMMA Haydarpasa Training Hospital, 81100, Kadikoy/Istanbul, Turkey.
Summary
Hyperbaric oxygen (HBO2) therapy at 2.5 ATA significantly reduces intraocular pressure (IOP) during treatment. IOP levels returned to normal after the hyperbaric oxygen therapy concluded.
Area of Science:
- Ophthalmology
- Physiology
- Hyperbaric Medicine
Background:
- The impact of hyperoxia on intraocular pressure (IOP) is documented in animal and human studies.
- Changes in IOP during routine hyperbaric oxygen (HBO2) therapy in patients remain unclear.
Purpose of the Study:
- To investigate IOP fluctuations in patients undergoing HBO2 therapy at 2.5 ATA.
- To determine if HBO2 therapy affects IOP in a clinical setting.
Main Methods:
- Fifty-six patients undergoing HBO2 therapy for various conditions were enrolled.
- Bilateral IOP measurements were taken using a Tono-pen XL tonometer before, during, and after HBO2 therapy at 2.5 ATA.
Main Results:
- Average IOP decreased significantly from 14.85 mmHg pre-therapy to 13.00 mmHg during therapy.
- IOP returned to baseline levels (14.74 mmHg) after the HBO2 therapy session.
- The observed IOP decrease during therapy was statistically significant but of minor physiological importance for patients with normal baseline IOP.
Conclusions:
- HBO2 therapy at 2.5 ATA causes a significant, albeit temporary, reduction in IOP.
- The IOP changes observed during therapy are not clinically significant for individuals with normal baseline IOP.
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