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Related Experiment Videos

Cervical herpes zoster and delayed brainstem infarction.

J Willeit1, E Schmutzhard

  • 1Department of Neurology, University of Innsbruck, Austria.

Clinical Neurology and Neurosurgery
|January 1, 1991
PubMed
Summary

Varicella-zoster virus can cause rare central nervous system (CNS) angiitis. This case highlights VZ-angiitis presenting with ventral pons infarction after cervical herpes zoster.

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Area of Science:

  • Neurology
  • Infectious Diseases
  • Neuroimmunology

Background:

  • Varicella-zoster virus (VZV) is a known cause of central nervous system (CNS) infections.
  • CNS angiitis is a rare but serious complication associated with VZV reactivation.
  • Herpes zoster ophthalmicus is a common presentation, often leading to hemispheric infarction.

Observation:

  • This report details the first documented case of VZV-angiitis.
  • The patient presented with symptoms following cervical herpes zoster.
  • The infarction occurred in the ventral pons, a less common site for VZV-related CNS events.

Findings:

  • VZV reactivation led to angiitis and subsequent infarction in the ventral pons.
  • This presentation differs from the typical herpes zoster ophthalmicus with contralateral hemiplegia.
  • Cervical herpes zoster can precede CNS involvement in VZV-angiitis.

Implications:

  • This case expands the spectrum of CNS complications associated with VZV.
  • It underscores the importance of considering VZV in the differential diagnosis of CNS angiitis, even with atypical presentations.
  • Early recognition and treatment of VZV-angiitis are crucial to prevent severe neurological deficits.

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