Related Experiment Video
Updated: Aug 9, 2026

Three-Dimensional Cell Culture Models to Investigate the Epithelial Barrier in Eosinophilic Esophagitis
Published on: May 10, 2024
[Abdominal pain, indigestion and eosinophilia]
Isabel Ittig Boo1, Lorenz Risch, Ingmar A F M Heijnen
1Zentrum für Labormedizin, Kantonsspital Aarau, 5001 Aarau.
Abstract:
A 56 years old swiss man suffers of recurrent abdominal cramps with episodes of diarrhea and profuse expectorations. The routine laboratory shows principally a massive eosinophilia and elevated IgE in peripheral blood. After excluding the most frequent causes of eosinophilia, further laboratory investigations shows increased levels antinuclear and anti-SSA antibodies, elevated IgG4, increased pancreatic amylase and intestinal eosinophilia. We consider two etiologies: the hypereosinophilic syndrome, diagnostic of exclusion, and the autoimmune pancreatitis. Although we have not sufficient arguments in favour of an autoimmune pancreatitis, these two entities present some similar points.
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