Structure and regulation of G protein-coupled receptors: the beta 2-adrenergic receptor as a model

Discovery of a functionally selective ghrelin receptor (GHSR1a) ligand for modulating brain dopamine.

Proceedings of the National Academy of Sciences of the United States of America·2022

The physiological relevance of functional selectivity in dopamine signalling.

International journal of obesity supplements·2016

Daytime spikes in dopaminergic activity drive rapid mood-cycling in mice.

Molecular psychiatry·2015

Increased expression of the dopamine transporter leads to loss of dopamine neurons, oxidative stress and l-DOPA reversible motor deficits.

Neurobiology of disease·2014

Novel roles for β-arrestins in the regulation of pharmacological sequestration to predict agonist-induced desensitization of dopamine D3 receptors.

British journal of pharmacology·2013

N-aryl piperazine metabotropic glutamate receptor 5 positive allosteric modulators possess efficacy in preclinical models of NMDA hypofunction and cognitive enhancement.

The Journal of pharmacology and experimental therapeutics·2013

Bilateral macronodular and micronodular hyperplasia: Biochemical, radiological and genetic diagnosis.

Vitamins and hormones·2026

ACTH independent Cushing's syndrome: Diagnosis and etiology.

Vitamins and hormones·2026

Biochemical diagnosis of hypercortisolism: When and how?

Vitamins and hormones·2026

New tools for the diagnosis of hypercortisolism.

Vitamins and hormones·2026

Cardiometabolic comorbidities in overt Cushing's syndrome.

Vitamins and hormones·2026

Molecular profile of Cushing's syndrome.

Vitamins and hormones·2026

Lipid composition-driven sorting of ABHD5 between monolayer and bilayer surfaces.

Journal of lipid research·2026

GlycoMAC: A Multiscale Metabolic-Glycosylation Framework for Predicting Glycosylation Across Conditions in Mammalian Cell Cultures.

Biotechnology and bioengineering·2026

A passive protein environment offsets RNA folding energetics in cells.

bioRxiv : the preprint server for biology·2026

Single-molecule fluorescence methods for visualizing the central dogma.

Current opinion in structural biology·2026

Sequestosome 1 (SQSTM1/p62) at the nexus of genome integrity maintenance, proteostasis regulation and organellar homeostasis.

Biological chemistry·2026

Insights into the Solution Structure and Oligomeric State of Fructose-1,6-bisphosphate Aldolase and Pyruvate Kinase from Nakaseomyces glabratus by Small-Angle X‑ray Scattering (SAXS) and AlphaFold Prediction.

ACS omega·2026

Related Experiment Videos

Structure and regulation of G protein-coupled receptors: the beta 2-adrenergic receptor as a model

Related Concept Videos

Discovery of a functionally selective ghrelin receptor (GHSR1a) ligand for modulating brain dopamine.

The physiological relevance of functional selectivity in dopamine signalling.

Daytime spikes in dopaminergic activity drive rapid mood-cycling in mice.

Increased expression of the dopamine transporter leads to loss of dopamine neurons, oxidative stress and l-DOPA reversible motor deficits.

Novel roles for β-arrestins in the regulation of pharmacological sequestration to predict agonist-induced desensitization of dopamine D3 receptors.

N-aryl piperazine metabotropic glutamate receptor 5 positive allosteric modulators possess efficacy in preclinical models of NMDA hypofunction and cognitive enhancement.

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GlycoMAC: A Multiscale Metabolic-Glycosylation Framework for Predicting Glycosylation Across Conditions in Mammalian Cell Cultures.

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Sequestosome 1 (SQSTM1/p62) at the nexus of genome integrity maintenance, proteostasis regulation and organellar homeostasis.

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Structure and regulation of G protein-coupled receptors: the beta 2-adrenergic receptor as a model

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