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Updated: Aug 2, 2026
A Protocol for Analyzing Hepatitis C Virus Replication
Published on: June 26, 2014
Genotype distribution amongst hepatitis C patients in The Netherlands
M J de Vries1, B te Rijdt, C M J van Nieuwkerk
1Roche Nederland BV, Woerden, The Netherlands. martin.de_vries@roche.com
Background:
The prevalence of the genotypes of the hepatitis C virus (HCV) differs according to geographical location. In the United States and in European countries, the majority of patients are infected with genotype 1, 2 or 3. There is a lack of data on the distribution of HCV genotypes in The Netherlands.
Methods:
The current survey determined the distribution of HCV genotypes amongst recently genotyped patients seen by physicians treating hepatitis C in The Netherlands.
Results:
Almost half of the 351 patients (49.3%) were infected with genotype 1. Genotype 3 was the second most dominant genotype with a prevalence of 29.3%. Genotypes 2 and 4 were found in 9.7 and 10.5% of the patients, respectively. For 61.5% of the patients (n=216), the subtype was available. For genotype 1 the prevalence of subtype 1a and 1b was very similar, while for genotype 3 a large majority of patients were infected with subtype 3a.
Conclusion:
This survey gives the first estimation of the distribution of HCV genotypes amongst unselected HCV patients in The Netherlands.
