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Updated: Jul 17, 2026
14:58
Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations
Published on: October 20, 2017
A 21-year-old female with a third ventricular tumor
Brain Pathology (Zurich, Switzerland)
|April 15, 2006
Summary
This study reports the first case of a benign schwannoma in the third ventricle, a rare intraventricular tumor. This finding expands the understanding of rare brain tumors and their origins.
Area of Science:
- Neuro-oncology
- Neuropathology
Background:
- Intraventricular tumors are rare, with Schwann cell tumors being exceptionally uncommon.
- Schwann cell tumors typically arise from peripheral nerves, making intraventricular locations unusual.
Observation:
- A 21-year-old female presented with tinnitus, vertigo, and nausea.
- MRI revealed a contrast-enhancing mass in the third ventricle.
- Histopathology confirmed a World Health Organization grade I benign schwannoma.
Findings:
- This is the first reported case of a schwannoma specifically located in the third ventricle.
- Only nine intraventricular Schwann cell tumors have been documented previously, mostly benign.
- The exact origin of these tumors remains unclear, possibly from autonomic nerves or ectopic cells.
Implications:
- This case contributes to the limited literature on intraventricular Schwann cell tumors.
- Distinguishing intraventricular schwannoma from other spindle cell tumors like pilocytic astrocytoma is crucial.
- Further research is needed to elucidate the origin and behavior of these rare tumors.
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